Technology - Google News

Zoom photo comparison: Pixel 5 vs. Pixel 4 - Android Police

Posted: 25 Oct 2020 07:00 AM PDT

Google's latest, greatest Pixel phone is really only one of those things—after catching flack for the poor value of the Pixel 4, Google scaled back on the Pixel 5. Gone are features like Face Match, Ambient EQ, and perhaps most importantly, the telephoto camera. Instead, the Pixel 5 has a wide/ultrawide combo, and some people might prefer that. However, it's a disadvantage if you want to take photos of things from a distance.

We've got six sets of photos, three indoors and three outdoor, taken on the Pixel 4 and Pixel 5. Each set includes a 2x, 4x, and 6x zoom shot. On the Pixel 5, these are all taken with the main camera and cropped with magical AI technology. The Pixel 4 uses its 2x optical zoom module to boost the clarity, and you can tell the difference in a lot of images. However, the Pixel 5 holds its own surprisingly well, particularly inside where the Pixel 4's narrower aperture hurts it.

Note, all sliders have Pixel 4 on the left and Pixel 5 on the right.

Indoors

2x zoom

4x zoom

6x zoom

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6x zoom

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6x zoom

One thing of note about the indoor shots; the Pixel 5 pics are a bit brighter. That's because the Pixel 4's telephoto camera has a narrower f/2.4 aperture vs. the primary camera's f/1.7. The Pixel 5 uses that module for all zoom shots, unlike the Pixel 4. Last year's phone sticks with the main sensor for indoor shots without sufficient light, but we've made sure our samples were all taken with the telephoto. Predictably, the Pixel 4 can extract more detail, which is particularly noticeable at 6x. The Pixel does an admirable job at 2x and 4x, helped by the larger aperture, but the images look a bit unnatural to me.

Outdoors

The differences are more noticeable in the outdoor shots as there's more light to compensate for the Pixel 4's narrower telephoto aperture. The 2x zoom shots are still a bit of a toss-up (which is impressive photo processing for the Pixel 5), but there's a definite drop in clarity at 4x and especially 6x. Again, the Pixel 4 is on the left of the slider and the Pixel 5 is on the right.

2x zoom

4x zoom

6x zoom

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6x zoom

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If I had my choice of sensors on the Pixel 5, I'd pick telephoto over ultrawide. While Google's super-res zoom can do some amazing things, it's even better with real optical zoom in the mix. In a perfect world, the Pixel would have wide, ultrawide, and telephoto sensors. Alas, Google isn't great at making high-end phones, and ultrawide sensors are cheaper.

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A family that raised $2 million for their baby's life-saving medical treatment has received it for free - CNN

Posted: 25 Oct 2020 03:02 AM PDT

Lucy Van Doormaal, now 7 months old, was born with spinal muscular atrophy (SMA), a genetic disease that causes infants' muscles to waste away, potentially killing them before age 2.

After her family raised nearly $2 million to pay for a potentially life saving treatment, administered as a one-time infusion into a vein, Lucy was randomly selected by drug company Novartis Gene Therapies to receive the treatment for free through its Managed Access Program (MAP).

"We were totally shocked, we didn't expect this outcome but we were just so happy because our single goal was providing the treatment to Lucy," Laura Van Doormaal, Lucy's mom, told CNN. "This has been a traumatic experience, having to fight for treatment and put our life out there to fund it, so this is really a relief."

Lucy, her parents Scott and Laura Van Doormaal, and her 3-year-old brother Sullivan.

SMA is an inherited disorder stemming from a defective gene that leads to the death of nerve cells responsible for moving the muscles that allow people to walk, talk, breathe and swallow, according to the National Institute of Neurological Disorders and Stroke.

Lucy has type 1 SMA, the most aggressive and severe form of the disease which leaves her nearly unable to crawl, swallow or even breathe. Lucy's only chance of surviving past her second birthday was Zolgensma, one of the only approved treatments for SMA.

Another chance of survival

Since receiving the treatment, Van Doormaal said Lucy has already shown significant improvement.

"We noticed an immediate difference. The biggest changes are her head control, really quickly after the treatment she was able to hold her head up which is something she's never done before. She can sit with some support and hopefully one day she'll crawl," Van Doormaal said.

"Maybe one day she'll even walk. That's really an optimistic dream, I know, but we like to have high expectations and we don't want to hold her back."

The gene therapy treatment, which comes with the hefty price tag of $2.125 million, alters the patient's biology -- but it's still not a guaranteed cure.

Zolgensma replaces a working copy of the defective gene into those nerve cells before they die and symptoms develop.

The treatment is available in the US and other countries, but is not yet approved in Canada. However, British Columbia Children's Hospital was able to provide Lucy with treatment, Van Doormaal said.

In 2020, Novartis launched a Managed Access Program to provide 100 eligible patients with SMA under the age of 2 in countries where Zolgensma is not approved.

"While we aren't providing specific numbers at this time, we can confirm that already the program has enabled children across Asia, Australia, Europe and North America (including Canada) to receive treatment who may not have otherwise had access to the therapy," a Novartis Gene Therapies company spokesperson told CNN.

Learning to live with SMA

On April 1, 2020, at 7:35 p.m., Lucy was born at a hospital in Vancouver, weighing 7 pounds and 13 ounces, with big bright blue eyes. Right away, she took to sucking her thumb.

She was a perfectly healthy baby until two weeks later, when Lucy's parents began to notice her struggling to breathe and move her arms. When she was no longer able to bring her thumb to her mouth, they knew something was very wrong.

"When we first took her home, we were in newborn bliss. Just absolutely in love with her. She was a great baby," Van Doormaal said. "But we started to realize her movement was declining. She had trouble breathing and eating. When she was five weeks old, she was diagnosed with spinal muscular atrophy."

Lucy at the hospital before receiving Zolgensma.

Since SMA results in severe respiratory issues, Lucy sleeps hooked to a BiPAP (Bilevel Positive Airway Pressure) machine, a non-invasive ventilator, to help her breathe. Her family also uses an oximeter to monitor her pulse and blood oxygen levels.

Because Lucy has lost the ability to feed on her own through her mouth, she has also undergone surgery to receive a gastrostomy tube.

While every child responds differently to Zolgensma, there is a chance Lucy will be able to outgrow the gastrostomy tube. She may also be able to hit other critical milestones, like sitting, rolling, crawling and maybe one day even walking. It might also strengthen her breathing and swallowing muscles, which will have the biggest impact on her quality of life.

"Now that we got the treatment we can focus on her recovery and her progress and enjoying her as a baby, but we also now have to face the grief we are feeling from the diagnosis and process what our new life looks like," Van Doormaal said. "These are all healthy things that needed to happen, so we definitely feel so much more hopeful about our future."

The money raised through the family's GoFundMe has been donated to other babies with SMA who needed Zolgensma as well as a few charities, with the rest of the funds going towards Lucy's future medical needs.

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